Disease Areas
Depression is a debilitating illness that is one of the leading contributors to disability worldwide1 and the second leading cause of disability in the U.S.2 Postpartum depression, one of the most common medical complications in pregnancy, is estimated to affect approximately one in eight women who have given birth in the U.S.3,4
Depression impacts a wide range of people, and in recent years, the incidence of mental health cases have increased dramatically.5 The symptoms can vary widely, affecting people in different ways. Despite more than 20 therapeutic options, two out of three patients fail to achieve remission with the current standard of care.6
We are committed to advancing innovative research on the pathophysiology of mental health conditions. It is estimated that fewer than one-third of people living with depression receive adequate treatment and approximately 500,000 women annually are affected by postpartum depression.4,6
We are working to advance the treatment of depression and pioneer solutions for those living with or impacted by these diagnoses.
We are focused on revolutionizing the care of depression and exploring opportunities where great unmet need remains to change how mental health conditions are treated. As we work to develop new approaches to treating depression, we also aim to address the social stigmas of mental illness by working with the community through dialogue, raising awareness and creating understanding.
Mental health stigma can cause those living with depression to feel ashamed and isolated. By sharing her family’s battles with major depressive disorder, Monica hopes to raise awareness and encourage acceptance.
After Caitlin had her first baby, she thought the experience she was having was the “normal baby blues.” She felt overwhelmed and disconnected from her son and didn’t understand why.
Many people experiencing depression may have trouble recognizing the signs and symptoms, leading to challenges in diagnosing and treating the disease. Mona Kotecha, M.D., executive medical director of our emerging neurosciences development unit, explains more about the impact of depression and the need to advance innovation in mental health.
The National Alliance on Mental Illness support groups offer the opportunity to share experiences and gain support from others affected by mental health conditions like depression (for U.S. residents). Learn more and find a support group near you.
DBSA offers peer-based, wellness-oriented support and empowering services online 24/7, in audio and video casts, in printed materials, in local support groups, in their chapters, and in mental health care facilities across America.
Chapters and Support Groups | Depression and Bipolar Support Alliance
Mental Health America promotes mental health as a critical part of overall wellness. The organization works to address mental health and mental illness through advocacy, education, research and services.
Postpartum Support International provides resources to help families, providers and communities learn about the emotional and mental health of childbearing families.
In the United States, an estimated 1 in 8 mothers experience symptoms of postpartum depression, which equates to approximately 500,000 cases annually.4
Approximately 1 in 5 individuals in the United States will experience major depressive disorder at some point in their lives.7
Depression alone affects approximately 280 million people worldwide – impacting both lives and livelihoods.8